Workgroup “Membrane Trafficking and EVs”

Francesca Botanelli
bottanelli@zedat.fu-berlin.de

Kerstin Menck
Kerstin.Menck@ukmuenster.de

Summary

Membrane trafficking refers to the complex network of processes that regulate the transport of molecules and organelles within cells, ensuring proper cellular organization, signaling, and communication. This includes the movement of proteins, lipids, and other cargo between different cellular compartments, such as the ER, Golgi, or plasma membrane. Extracellular vesicles (EVs), on the other hand, are small, membrane-bound particles released by cells into their surroundings, playing a crucial role in intercellular communication and the exchange of biological information. They can carry a wide range of molecular cargo, including proteins, lipids, and nucleic acids, and have been implicated in various physiological and pathological processes. The biogenesis and release of EVs rely heavily on intracellular membrane trafficking pathways. The formation and loading of EVs with specific cargo involves intricate trafficking mechanisms, making the study of membrane trafficking essential for understanding EV biology. Conversely, the analysis of EVs can provide valuable insights into the regulation and dysfunction of membrane trafficking processes. Our focus group aims to bring together researchers from diverse backgrounds to explore the intricacies of membrane trafficking and extracellular vesicles, fostering collaboration, knowledge sharing, and innovation in this exciting field. Join us to explore the fascinating world of cellular logistics and communication!