Cell News | Issue 01, 2017 - page 41

Cell News 3/2016
Research Training Group 1459
The interdisciplinary
Research Training Group (GRK) 1459 “Sorting and Interactions between Proteins
of Subcellular Compartments”
) was founded in 2008 and consists of scientists from
the University Medical Center Hamburg-Eppendorf, the Institute of Biochemistry at the University Kiel,
and the Bernhard-Nocht-Institute for Tropical Medicine in Hamburg. Eleven PhD students and five MD
students are funded by the Deutsche Forschungsgemeinschaft (DFG). The general topic of the
Research Training Group is sorting and transport of selected proteins within the Golgi apparatus and
endosomal compartments. Missorted proteins may lead to loss of function in their target organelles,
which may affect the wellbeing of the cell and the organism as a whole. By focussing on selected
model proteins, basic mechanisms of the biogenesis of intracellular compartments as well as the
balance of membrane transport between organelles and the interplay between cytosolic and
membrane proteins will be investigated. The majority of projects address sorting and transport
processes under pathological conditions in cells derived from patients or mouse models of human
diseases or cells infected by bacteria or in parasite cells.
Every two years the graduate students of the GRK 1459 are preparing the International Symposium on
Protein Trafficking in Health and Disease
. This year the 4
International Symposium will take
place from
June 7th to 9th 2017 in Hamburg, Germany
and again leading experts in the field of
protein trafficking could be confirmed as speakers (
). The GRK
1459 invites PhD students and young postdocs from all over Europe to come to Hamburg and
participate in an exciting program and learn about the newest findings in vesicular transport,
autophagy and protein quality control, the endo-lysosomal system and infection.
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