Cell News 01/2019
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Prof. Vousden discovered MDM2 as a decisive regulator of p53
expression and uncovered how p53 induces cell death and
regulates cell metabolism. Her work has significantly con-
tributed to our current understanding of p53 as ‘the guardian
of the genome’ and of its role in tumor development. Volker
Dötsch (Frankfurt am Main) acknowledged her research and
her personality in his laudatory speech. In her Honorary Medal
Lecture, Prof. Vousden summarized the manifold aspects of p53
not only as central modulator of cell survival and death, but
also as regulator of the cell’s oxidative state. The lecture was
highly appreciated by the audience and followed by a lively and
inspiring discussion.
The support of young scientist is a key concern of the STS. In
2018, nine travel grants were donated to Master or MD/PhD
students who had actively applied for this funding. One of
the travel grants was sponsored by Biomol, the Silver Spon-
sor of the meeting. Moreover, seven poster prizes to a total
value of 750 € were awarded to the most excellent poster
presentations, which had been selected by the chair people of
the various workshops. To honor excellent research by a post
doc or junior principal investigator, the STS Science Award
is granted since 2005. This year, Dirk Brenner (Luxembourg,
LU) received this prize for his comprehensive research on the
glutathione-dependent regulation of metabolic responses in
B and T cells. The award to a total sum of 1,500 € was donat-
ed by the STS and OMNI Life Science GmbH. Finally, on the
occasion of the STS Joint Meeting the GBM announces the
GBM Innovation Award for Young Scientists. The Award (500
€) is meant to honor young scientists working on an innovative
and interesting method in the field of signal transduction. The
award jury consisting of the speakers of the GBM-Study Groups
“Biochemical Pharmacology and Toxicology” and “Receptors
and Signal Transduction” selected Theresia Gutmann (Dresden)
to receive the award for embedding purified full-length insulin
receptors in so-called lipid nanodiscs and directly visualizing
the conformational change of the receptor induced by insulin.
This minimal
in vitro
system is a valuable technique for ana-
lyzing signaling mechanisms of the insulin receptor and other
receptor tyrosine kinases.
Lastly, we would like to thank our industrial sponsors and
MDPI
) as
well as our academic sponsors for having supported the 22
nd
STS Meeting. The preparations of the 23
rd
STS Meeting have
already started. The meeting will take place once more at the
Leonardo Hotel in Weimar from 4 - 6 November 2019. Further
details and regular updates on the schedule and program of the
meeting can be found at
and on the
STS Facebook account.
Prof. Dr. Klaudia Giehl
(STS Council)
Justus-Liebig-Universität Gießen
Signaltransduktion zellulärer Motilität
Medizinisches Forschungszentrum Seltersberg
Aulweg 128 – ForMed
35392 Gießen
Email:
Karen Vousden (left) receiving the STS Honorary Medal from
Katharina Kubatzky (STS president, right)
MEETING REPORT
