Cell News 01/2020
10
Selected reading:
Dias Gomes M*, Letzian S*, Saynisch M, and Iden S. Polarity signaling ensures epidermal homeostasis by cou-
pling cellular mechanics and genomic integrity.
Nat Commun
2019 Jul 29;10(1):3362
Vorhagen S*, Kleefisch D*, Persa OD, Graband A, Schwickert A, Saynisch M, Leitges M, Niessen CM#, and
Iden S
#
. Shared and independent functions of aPKClambda and Par3 in skin tumorigenesis.
Oncogene
, 2018
Sep;37(37):5136-5146 (*shared first/
#
corresp. authors)
Mescher M*, Jeong P*, Knapp SK, Rübsam M, Saynisch M, Kranen M, Landsberg J, Schlaak M, Mauch C, Tüting T,
Niessen CM, and Iden S. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant
melanoma.
J Exp Med
, 2017 Feb;214(2):339-358
Ali NJA, Dias Gomes M, Bauer R, Brodesser S, Niemann C, and Iden S. Essential role of polarity protein Par3 for
epidermal homeostasis through regulation of barrier function, keratinocyte differentiation and stem cell main-
tenance.
J Invest Dermatol
2016 Dec;136(12):2406-2416.
Iden S+, van Riel WE, Schäfer R, Song J-Y, Hirose T, Ohno S, Collard JG. Tumor Type-Dependent Function of the
Par3 Polarity Protein in Skin Tumorigenesis. Cancer Cell 2012 Sep;22(3):389-403. (
+
: corresp. author)
Iden S and Collard JG. Crosstalk between small GTPases and polarity proteins in cell polarization.
Nat Rev Mol
Cell Biol
2008 Nov;9(11):846-59
Prof. Dr. Ralf Jungmann
as Vice CEO
Date of birth: 14.05.1981
Max Planck Institute of Biochemistry and Ludwig Maximilian University Munich
Education/career:
2001–2006: Study of Physics at Saarland University and UC Santa Barbara; 2007–2010:
Graduate student with Prof. Dr. Friedrich Simmel at Technical University Munich; 2011–
2014: Postdoc with Prof. Dr. Peng Yin and Prof. Dr. William Shih at the Wyss Institute for
Biologically Inspired Engineering at Harvard University. Since 2014: Group Leader at the
Ludwig Maximilian University Munich and the Max Planck Institute of Biochemistry; Since 2016: Professor for
Physics at LMU Munich
Memberships:
DGZ, DPG
Research areas:
DNA Nanotechnology and Super-resolution Microscopy
Selected reading:
S. Strauss, R. Jungmann.
Up to 100-fold speed-up and multiplexing in optimized DNA-PAINT
.
Nature Methods
(2020). 17: 789-791
F. Schueder, J. Stein, F. Stehr, A. Auer, B. Sperl, M.T. Strauss, P. Schwille, R. Jungmann.
An order of magnitude
faster DNA-PAINT imaging by optimized sequence design and buffer conditions.
Nature Methods
(2019). 16:
1101–1104
F. Frottin, F. Schueder, S. Tiwary, R. Gupta, R. Koerner, T. Schlichthaerle, J. Cox, R. Jungmann°, F.U. Hartl°, M.S.
Hipp°
The nucleolus functions as a phase-separated protein quality compartment
Science
(2019). 365: 342-347
S. Strauss, P.C. Nickels, M.T. Strauss, V.J. Sabinina, J. Ellenberg, J.D. Carter, S. Gupta, N. Janjic, R. Jungmann.
Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging
.
Nature Methods
(2018). 15:
685–688
F. Schueder, J. Lara-Guitérrez, B.J. Beliveau, S.K. Saka, H.M. Sasaki, J.B. Woehrstein, M.T. Strauss, H. Grabmayr,
P. Yin°, R. Jungmann°.
Multiplexed 3D super-resolution imaging of whole cells using Spinning Disk Confocal
Microscopy and DNA-PAINT
.
Nature Communications
(2017). 8: 2090
DGZ ELECTION
