Cell News 1/2015
8
18:00 – 19:00 Carl Zeiss Lecture
Magdalena Götz (Munich, Germany):
Mechanisms of neurogenesis: from cell biology to neural
repair
19:00
Opening reception
Wednesday March 25, 2015
09:00 – 12:00 Symposia 1-4
09:00 – 12:00 Symposium S1: Centrosomes, spindle assembly
and cilia
Chairs: Thomas Müller-Reichert (Dresden, Germany) and
Gislene Pereira (Heidelberg, Germany)
09:00 – 09:30 Jan Brugues (Dresden, Germany):
Principles of meiotic spindle organization
09:30 – 10:00 Thomas Müller-Reichert (Dresden, Germany):
Three-dimensional reconstruction of the first mitotic
spindle in C. elegans reveals different populations of
microtubules with distinct properties
10:00 – 10:15 Bjorn Bakker: Deletion of the Mad2 spindle assembly
checkpoint gene causes chromosome instability with
differential effects on liver cancer and lymphoma
(short talk, A-108)
10:15 – 10:45 Coffee break
10:45 – 11:15 Jordan Raff (Oxford, UK):
How to build a centrosome during mitosis
11:15 – 11:45 Lotte Pedersen (Hillerød, Denmark):
Regulation of ciliary length and signalling by
kinesin-3 motors
11:45 – 12:00 Julian Nuechel: EHD4 controls resorption of primary cilia
during mitosis (short talk, A-104)
09:00 – 12:00 Symposium S2: Cellular chaperones and proteostasis
Chair: Jörg Höhfeld (Bonn, Germany)
09:00 – 09:30 Ulrich Hartl (Martinsried, Germany):
Chaperone mechanisms in protein folding and quality
control
09:30 – 10:00 Elke Deuerling (Konstanz, Germany):
Sorting right from wrong: How ribosome-associated
chaperones control protein transport processes
10:00 – 10:15 Simon Alberti:
Promiscuous interactions and protein disaggregases
determine the material state of stress-inducible RNP
granules (short talk, A-266)
10:15 – 10:45 Coffee break
10:45 – 11:15 Blanche Schwappach (Goettingen, Germany):
The GET pathway in proteostasis
11:15 – 11:45 Jörg Höhfeld (Bonn, Germany):
Chaperone-assisted proteostasis
11:45 – 12:00 Sebastian A. Leidel:
Misregulation of local translation rates leads to protein
aggregation defects (short talk, A-183)
09:00 – 12:00 Symposium S3: DNA repair and telomeres
Chairs: Katrin Paeschke (Wuerzburg, Germany) and
Brian Luke (Heidelberg, Germany)
09:00 – 09:30 Daniel Durocher (Toronto, Canada):
Cell cycle regulation of DNA double-strand break repair
09:30 – 10:00 Helle Ulrich (Mainz, Germany):
Dealing with DNA damage during replication
10:00 – 10:15 Amine Bouafia: p53 requires the stress sensor USF1 to
direct appropriate cell fate decision (short talk, A-221)
10:15 – 10:45 Coffee break
10:45 – 11:15 Jan Karlseder (La Jolla, USA):
Telomere function in mitosis: Complex interactions
determine cellular fate
11:15 – 11:45 Vincent Géli (Marseille, France): RPA prevents G4 struc-
tures at lagging strand telomeres to allow maintenance
of chromosome ends
11:45 – 12:00 Brian Luke (Heidelberg, Germany): Regulation of the
Mph1 helicase by Smc5/6 complex is crucial at short
telomeres and RNA-DNA hybrids
09:00 – 12:00 Symposium S4: Cell adhesion and mechanics
Chair: Thomas Magin (Leipzig, Germany)
09:00 – 09:30 Vania Braga (London, UK): Defining functional interac-
tions during biogenesis of epithelial junctions
09:30 – 10:00 Mechthild Hatzfeld (Halle, Germany): Functions of the
desmosomal protein plakophilin 1 in cell adhesion and
signaling
10:00 – 10:15 Jaap van Buul: A local VE-cadherin/Trio-based signaling
complex stabilizes endothelial junctions through Rac1
(short talk, A-105)
10:15 – 10:45 Coffee break
10:45 – 11:15 Ben Fabry (Erlangen, Germany): Adhesion, contraction,
or cell mechanics: which cell properties matter for
cancer cell invasion?
11:15 – 11:30 Antje Schaefer: Actin-binding proteins differentially
control endothelial cell stiffness to drive function of
the
β
2 integrin ligand ICAM-1 and neutrophil
transmigration (short talk, A-102)
11:30 – 12:00 Manuel Thery (Paris, France):
Force scaling in stress fibers
12:00 – 13:00 Lunch
12:00 – 13:00 Lunch Symposium 1: Carl Zeiss Microscopy GmbH –
München
The New ZEISS LSM 8 Family:
Revolutionize Your Confocal Imaging
Referent: Dr. Sebastian Wiesner
13:00 – 15:00 Poster Session 1
15:00 – 18:00 Plenary Session 2: Stem cells and cell fate
together with the Dutch Society for Cell Biology
Chairs: Jacco van Rheenen (Utrecht, The Netherlands)
and Carien Niessen (Cologne, Germany)
15:00 – 15:30 Hans Clevers (Utrecht, The Netherlands):
Wnt signaling, Lgr5 stem cells and cancer
15:30 – 16:00 Timm Schroeder (Basel, Switzerland): Long-term single
cell quantification: New tools for old questions
International Meeting