rentiation of mammalian skin. Nature 437, 275-280.
Lee, C.Y., Robinson, K.J., and Doe, C.Q. (2006). Lgl, Pins and aPKC regulate neuroblast self-
renewal versus differentiation. Nature 439, 594-598.
Leitges, M., Sanz, L., Martin, P., Duran, A., Braun, U., Garcia, J.F., Camacho, F., Diaz-Meco,
M.T., Rennert, P.D., and Moscat, J. (2001). Targeted disruption of the zetaPKC gene results in
the impairment of the NF-kappaB pathway. Mol Cell 8, 771-780.
Li, R., and Bowerman, B. (2010). Symmetry breaking in biology. Cold Spring Harb Perspect
Biol 2, a003475.
Macara, I.G., and Mili, S. (2008). Polarity and differential inheritance--universal attributes
of life? Cell 135, 801-812.
Martin, P., Villares, R., Rodriguez-Mascarenhas, S., Zaballos, A., Leitges, M., Kovac, J., Sizing,
I., Rennert, P., Marquez, G., Martinez, A.C., Diaz-Meco, M.T., and Moscat, J. (2005). Control
of T helper 2 cell function and allergic airway inflammation by PKCzeta. Proc Natl Acad Sci
U S A 102, 9866-9871.
McCaffrey, L.M., and Macara, I.G. (2009). Widely conserved signaling pathways in the esta-
blishment of cell polarity. Cold Spring Harb Perspect Biol 1, a001370.
Mertens, A.E., Rygiel, T.P., Olivo, C., van der Kammen, R., and Collard, J.G. (2005). The Rac
activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and
activation of the Par polarity complex. J Cell Biol 170, 1029-1037.
Moscat, J., Diaz-Meco, M.T., and Wooten, M.W. (2009). Of the atypical PKCs, Par-4 and
p62: recent understandings of the biology and pathology of a PB1-dominated complex. Cell
Death Differ 16, 1426-1437.
Nelson, W.J. (2003). Adaptation of core mechanisms to generate cell polarity. Nature 422,
766-774.
Niessen, M.T., Iden, S., and Niessen, C.M. (2012). The in vivo function of mammalian cell
and tissue polarity regulators--how to shape and maintain the epidermal barrier. J Cell Sci
125, 3501-3510.
Roignot, J., Peng, X., and Mostov, K. (2013). Polarity in mammalian epithelial morphogenesis.
Cold Spring Harb Perspect Biol 5.
Rosse, C., Linch, M., Kermorgant, S., Cameron, A.J., Boeckeler, K., and Parker, P.J. (2010). PKC
and the control of localized signal dynamics. Nat Rev Mol Cell Biol 11, 103-112.
Sengupta, A., Duran, A., Ishikawa, E., Florian, M.C., Dunn, S.K., Ficker, A.M., Leitges, M.,
Geiger, H., Diaz-Meco, M., Moscat, J., and Cancelas, J.A. (2011). Atypical protein kinase C
(aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity
and blood formation. Proc Natl Acad Sci U S A 108, 9957-9962.
Simons, M., and Mlodzik, M. (2008). Planar cell polarity signaling: from fly development to
human disease. Annu Rev Genet 42, 517-540.
Soloff, R.S., Katayama, C., Lin, M.Y., Feramisco, J.R., and Hedrick, S.M. (2004). Targeted dele-
tion of protein kinase C lambda reveals a distribution of functions between the two atypical
protein kinase C isoforms. J Immunol 173, 3250-3260.
Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat
Genet 21, 70-71.
St Johnston, D., and Ahringer, J. (2010). Cell polarity in eggs and epithelia: parallels and
diversity. Cell 141, 757-774.
Suzuki, A., and Ohno, S. (2006). The PAR-aPKC system: lessons in polarity. J Cell Sci 119,
979-987.
Watt, F.M., and Jensen, K.B. (2009). Epidermal stem cell diversity and quiescence. EMBO
Mol Med 1, 260-267.
Yang, J.Q., Leitges, M., Duran, A., Diaz-Meco, M.T., and Moscat, J. (2009). Loss of PKC lamb-
da/iota impairs Th2 establishment and allergic airway inflammation in vivo. Proc Natl Acad
Sci U S A 106, 1099-1104.
Das Non Plus Ultra
für die Probenlagerung
Der -86 °C BINDER Ultra-Tiefkühlschrank
bietet maximale Prozesssicherheit und
Bedienerfreundlichkeit durch innovative Lösungen.
Ultra sicher.
Ultra zuverlässig.
Ultra benutzerfreundlich.
BINDER GmbH
Im Mittleren Ösch 5 D-78532 Tuttlingen
Telefon:
07462 / 2005 - 0 |
Fax:
07462 / 2005 - 100
|
