Cell News 2/2014
25
Tuesday, June 10th, 2014
17:00 – 19:00 Opening Lectures
Keynote Lecture 1: Leslie Leinwand (Boulder, USA): Molecular basis of inherited cardiomyopathies
Keynote Lecture 2: Peter Gunning (Sydney, Australia): Diversity of the actin cytoskeleton and its implications for tropomyosin based muscle disease
20:00
Dinner and get together
Wednesday, June 11th, 2014
Session 1: Intermediate Filaments; Chair: Harald Herrmann (Heidelberg, Germany)
08:30
Gisèle Bonne (Paris, France): Lamin A/C myopathies: molecular insight from cell and animal models
09:00
Omar Skalli (Memphis, USA): The role of synemin in normal and diseased muscle
09:30
Yassemi Capetanaki (Athens, Greece): Desmin as a major player in Heart Failure
10:00
Rolf Schröder (Erlangen, Germany): The downstream pathology of point-mutated desmin: from aberrant localization and turnover of
intermediate filaments over decreased biomechanical stability of muscle fibers to myopathy and cardiomyopathy
talks selected from the abstracts
10:30
Ralf Bauer (Heidelberg, Germany): AAV-mediated cardiac transfer of the desmin cDNA ameliorates progression of cardiomyopathy in
desmin-deficient mice
10:45
Hendrik Milting (Bad Oeynhausen, Germany): No evidence for lysosomal degradation of mutant desmin causing severe
cardiomyopathies and cytosolic protein aggregates
10:30
Coffee and Discussion
Session 2: IF-Associated Proteins; Chair: Gisèle Bonne (Paris, France)
11:30
Gerhard Wiche (Vienna, Austria): Plectinopathies: from cell and animals models to potential treatments
12:00
Gloria Conover (Galveston, USA): Nebulin – getting it clear with desmin
talks selected from Abstracts
12:30
Petra Zugschwerdt (Heidelberg, Germany): How are intermediate filaments integrated into cellular structures by synemin and nestin?
12:45
Robert Stehle (Cologne, Germany): Biomechanical characterization of plectindeficient skinned fibres and myofibrils from mouse
psoas muscle
13:00
Lunch Break
14:00-15:30 Poster Session I with Coffee and Discussion
Session 3: Protein quality control; Chair: Rolf Schröder (Erlangen, Germany)
15:30
Roy Quinlan (Durham, UK): The functional role of alphaB-crystallin for muscle maintenance
16:00
Wolfgang Rottbauer (Ulm, Germany): VCP & VCP binding partners: lessons from functional genomics in zebrafish
16:30
Marco Sandri (Padova, Italy): Regulation of the autophagic system in striated muscle wasting
17:00
Jörg Höhfeld (Bonn, Germany): BAG3-mediated mechanotransduction is essential for muscle maintenance
17:30
Norbert Frey (Kiel, Germany): Novel pathways in protein degradation
18:00
Christoph Clemen (Cologne, Germany): VCP – PSMF1 interaction: a switching system to regulate 26S proteasome activity
18:30
Dinner
20:00
After-Dinner-Talk; Ueli Aebi (Basel, Switzerland): Actin: from Structural Plasticity to Functional Diversity
Future Meeting
Molecular Insight into Muscle Function and Protein Aggregate
Myopathies
10 – 13 July 2014, Potsdam
Organizers: Prof. Dr. Dieter O. Fürst, Institute for Cell Biology, University of Bonn
Prof. Dr. Harald Herrmann, Deutsches Krebsforschungszentrum Heidelberg
Prof. Dr. Rolf Schröder, University Hospital, Erlangen
Date:
Start: 10.06.2014, 15:00 Uhr; End: 13.06.2014, 13:00 Uhr
Venue:
Seminaris SeeHotel, Potsdam
